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Jack Sisson's Life Ethics Blog
We must find new ways through many ethical issues, especially regarding bioethics, medical ethics, and criminal justice. Jack Sisson's 'Life Ethics' blog focuses on numerous areas of concern, including the philosophical and ethical dilemmas surrounding stem-cell research, abortion, medical research, and health care.
Friday, March 30, 2012
Dangerous Drugs and Medical Devices Marketed to Women, Hurting Women
From Digital Journal:
Every day we hear about dangerous drugs and medical devices. The U.S. Food and Drug Administration (FDA) routinely reports on investigations, warnings, injuries and recalls. Unfortunately much of the press surrounding these drugs and devices fails to highlight the fact that a growing number of these products are injuring one specific group, women.
Tuesday, March 27, 2012
Prescription drugs can make good story but bad news
Sunday, March 25, 2012
Merck ponders next step for troubled heart drug
From USA Today:
Officials at drugmaker Merck & Co. say they will take more time to decide what to do about an experimental blood thinner that gave disappointing results in a second big study.
The study was aimed at preventing repeat heart attacks and strokes in people who had already suffered one or were in danger of one because of hardened arteries in their legs.
The drug, vorapaxar, lowered the risk of those problems but also raised the risk of major bleeding, including dangerous bleeding in the head, which largely canceled out the drug's benefit.
Results of the study were discussed Saturday at an American College of Cardiology conference in Chicago and published by the New England Journal of Medicine.
Merck had hoped vorapaxar would become a blockbuster alternative to Coumadin, sold generically as warfarin and one of the most commonly used heart drugs in the world. It's tough to get warfarin's dose right — too little and a clot can form and cause a heart attack; too much and dangerous bleeding can occur in the stomach or elsewhere in the body.
The company-sponsored study involved more than 26,000 patients in 32 countries. All were given usual heart medicines plus aspirin, and half also received daily vorapaxar pills.
Safety monitors stopped part of the study last year after seeing higher rates of bleeding in the head among people with a history of stroke who were on the experimental drug. The study continued in the rest of the participants.
After three years, about 9% of those given vorapaxar had suffered a heart attack or a stroke or had died from heart-related causes versus more than 10 percent of those not given the drug. Moderate or severe bleeding occurred in about 4% of those on vorapaxar versus just more than 2% of the others, said the study's leader, Dr. David Morrow of Brigham and Women's Hospital in Boston.
Among those with a history of heart attack — two-thirds of study participants — the drug had a net benefit, though, leaving the possibility that Merck might pursue seeking federal approval to sell it for these patients.
However, several experts not connected with the study said the drug's relatively modest benefit and likely high cost would make it a tough sell even if it were allowed on the market.
"This is not a drug that I would put in my personal medicine chest," said Dr. Eduardo Marban of Cedars-Sinai Medical Center in Los Angeles.
Merck officials said they would discuss the results with more scientists before deciding next steps.
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Friday, March 02, 2012
Planned Parenthood: How it Helped Me
From Arcadia Patch:
...What sent me to my local Planned Parenthood office recently was the contraception Mirena, an IUD that contains the hormone levonorgestrel, commonly used in birth control and the morning-after pill.
Roe v. Wade
Stem Cell Fight!
Bush the hypocrite
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