Blogs Articles Organizations Biography Jack's Book Contact Information Links

Navigation: SOS Sisson > Life Ethics Blog


Jack Sisson's Life Ethics Blog

We must find new ways through many ethical issues, especially regarding bioethics, medical ethics, and criminal justice. Jack Sisson's 'Life Ethics' blog focuses on numerous areas of concern, including the philosophical and ethical dilemmas surrounding stem-cell research, abortion, medical research, and health care.

 
A digitalized image of a stem cell near hair follicles
From Scientific American:

Over the past few months, we have been flooded with emails from distressed parents asking whether their deaf child will be able to hear one day.

With each new email comes a poignant story about a child whose world is silent. It is estimated that hearing loss affects 11% of school age children and even mild loss may adversely influence school performance, cognitive development and language acquisition. The most common type of hearing loss, sensorineural, is the result of injury to the hair cells of the inner ear’s Organ of Corti, most commonly due to infections, medication, noise and aging.

Hair cells are mechano-transducers which convert sound energy received from the outer and middle ear structures into an electrical signal which is then transmitted by the cochlear nerve to the brain. If enough of a human’s 17,000 hair cells are damaged, then sufficient sound energy cannot be transmitted to the brain, and the result is hearing loss. While birds and reptiles replace damaged hair cells, mammals normally do not.

Although hearing aids and cochlear implants, the two main treatment modalities for sensorineural hearing loss (SNHL), have helped millions with impaired hearing around the globe, these devices do not restore or repair hearing. The idea of a cure has long been a dream for many parents of deaf children and the professionals who work with them. The sad reality, however, is that SNHL is currently considered irreversible. With the emergence of regenerative medicine and stem cell therapy, however, that dream may at last be within reach.

The Food and Drug Administration (FDA) has recently approved our groundbreaking trial to evaluate the safety of using a child’s own cord blood stem cells to regenerate damaged cells in the inner ear and potentially restore the child’s hearing. This trial builds on Dr. Baumgartner’s prior success treating traumatic brain injury (TBI) with stem cells, and encouraging pre-clinical data from Italy showing that cochlear damage in mice may be repaired by transplantation of human umbilical cord hematopoietic stem cells (HSC).

In the mouse study, researchers administered HSC intravenously to a mammalian mouse model in which permanent hearing loss had been induced by ototoxic medication, noise or both. Hair cell regeneration and repair of the Organ of Corti was only observed in mice that received HSC transplants. This experiment provided a proof of concept for our trial by suggesting that under certain conditions, mammals, like birds and reptiles, could replace their damaged hair cells.

Continue reading.

Labels: , , , , , ,


Brain Pills
Roe v. Wade
Stem Cells
Stem Cell Fight!
Bearing Right
Moral Monkey?
Op-ed
Dave's site
Stem Stall
Screamers
Bush the hypocrite

June 2005   July 2005   August 2005   September 2005   October 2005   December 2005   March 2006   April 2006   May 2006   July 2006   August 2006   September 2006   October 2006   November 2006   January 2007   February 2007   March 2007   April 2007   May 2007   June 2007   July 2007   August 2007   September 2007   October 2007   November 2007   December 2007   January 2008   February 2008   March 2008   March 2009   November 2009   April 2010   October 2010   April 2011   May 2011   January 2012   February 2012   March 2012   April 2012   May 2012   June 2012   November 2012   December 2012   January 2013   February 2013   March 2013   April 2013   May 2013  

only sossisson.com

This page is powered by Blogger. Isn't yours?


  Link to us: Link to us!